ABHD10 Gene Summary [Human]
This gene encodes a mitochondrially-localized enzyme that acts in liver cells as a hydrolase. The encoded protein removes glucuronide from mycophenolic acid acyl-glucuronide. There is a pseudogene for this gene on chromosome 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | ABHD10 |
| Official Name | abhydrolase domain containing 10, depalmitoylase [Source:HGNC Symbol;Acc:HGNC:25656] |
| Ensembl ID | ENSG00000144827 |
| Bio databases IDs | |
| Aliases | abhydrolase domain containing 10, depalmitoylase, Mycophenolic acid acyl-glucuronide esterase, mitochondrial |
| Synonyms | ABH10, abhydrolase domain containing 10, abhydrolase domain containing 10, depalmitoylase, LOC103693563, RGD1308084 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ABHD10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Alpha/beta hydrolase family
- Serine aminopeptidase, S33
- glycosidase
- enzyme
- protein binding
- palmitoyl-(protein) hydrolase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- cytosol
- mitochondrial matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ABHD10 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- glucuronoside catabolic process
- cellular glucuronidation
- protein depalmitoylation
Cellular Component
Where in the cell the gene product is active
- mitochondrial matrix
- mitochondrion
- cytosol
Molecular Function
What the gene product does at the molecular level
- palmitoyl-(protein) hydrolase activity
- hydrolase activity, hydrolyzing O-glycosyl compounds