Abhd10 Gene Summary [Rat]

Predicted to enable hydrolase activity, hydrolyzing O-glycosyl compounds and palmitoyl-(protein) hydrolase activity. Predicted to be involved in protein depalmitoylation and xenobiotic metabolic process. Predicted to be located in cytosol. Predicted to be active in mitochondrion. Orthologous to human ABHD10 (abhydrolase domain containing 10, depalmitoylase). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Abhd10
Official Name
abhydrolase domain containing 10 [Source:RGD Symbol;Acc:1308084]
Ensembl ID
ENSRNOG00000054334
Bio databases IDs NCBI: 303953 Ensembl: ENSRNOG00000054334
Aliases abhydrolase domain containing 10
Synonyms ABH10, abhydrolase domain containing 10, abhydrolase domain containing 10, depalmitoylase, LOC103693563, RGD1308084
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Abhd10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Alpha/beta hydrolase family
  • Serine aminopeptidase, S33
  • glycosidase
  • enzyme
  • protein binding
  • palmitoyl-(protein) hydrolase

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • lung adenocarcinoma formation
  • lung adenocarcinoma
  • atrial fibrillation
regulated by
  • B lymphocytes
  • GALC
  • RGS4
  • hippocampal neurons
regulates
  • xenobiotic

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • cytosol
  • mitochondrial matrix

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Abhd10 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • glucuronoside catabolic process
  • cellular glucuronidation
  • protein depalmitoylation

Cellular Component

Where in the cell the gene product is active
  • mitochondrial matrix
  • mitochondrion
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • palmitoyl-(protein) hydrolase activity
  • hydrolase activity, hydrolyzing O-glycosyl compounds

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.