CABS1 Gene Summary [Human]

Predicted to enable calcium ion binding activity. Predicted to be involved in flagellated sperm motility and spermatogenesis. Predicted to be located in acrosomal vesicle and sperm principal piece. Predicted to be active in mitochondrial inner membrane and motile cilium. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
CABS1
Official Name
calcium binding protein, spermatid associated 1 [Source:HGNC Symbol;Acc:HGNC:30710]
Ensembl ID
ENSG00000145309
Bio databases IDs NCBI: 85438 Ensembl: ENSG00000145309
Aliases calcium binding protein, spermatid associated 1, casein-like phosphoprotein
Synonyms 4931407G18Rik, C4orf35, calcium binding protein, spermatid associated 1, calcium binding protein, spermatid specific 1, CLPH, NYD-SP26, Rsd6
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CABS1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Calcium-binding and spermatid-specific protein 1
  • calcium ion binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • diphtheria toxin
role in cell
  • motility

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • motile cilia
  • mitochondrial inner membrane
  • acrosome

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human CABS1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • sperm motility
  • spermatogenesis

Cellular Component

Where in the cell the gene product is active
  • motile cilium
  • acrosomal vesicle
  • sperm principal piece
  • mitochondrial inner membrane

Molecular Function

What the gene product does at the molecular level
  • calcium ion binding

Gene-Specific Assays for Results You Can Trust

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