POMZP3 Gene Summary [Human]
This gene appears to have resulted from a fusion of DNA sequences derived from 2 distinct loci, specifically through the duplication of two internal exons from the POM121 gene and four 3' exons from the ZP3 gene. The 5' end of this gene is similar to the 5` coding region of the POM121 gene which encodes an integral nuclear pore membrane protein. However, the protein encoded by this gene lacks the nuclear pore localization motif. The 3' end of this gene is similar to the last 4 exons of the zona pellucida glycoprotein 3 (ZP3) gene and the encoded protein retains one zona pellucida domain. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | POMZP3 |
| Official Name | POM121 and ZP3 fusion [Source:HGNC Symbol;Acc:HGNC:9203] |
| Ensembl ID | ENSG00000146707 |
| Bio databases IDs | |
| Aliases | POM121 and ZP3 fusion, POM-ZP3 fusion protein, POM121/ZP3 fusion protein |
| Synonyms | POM121 and ZP3 fusion |
| Species | Human, Homo sapiens |
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Endoplasmic Reticulum
- nuclear pores
- nucleoplasm
- nuclear envelope
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human POMZP3 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nuclear membrane
- nucleoplasm