SLC12A9 Gene Summary [Human]
Predicted to enable potassium:chloride symporter activity. Predicted to be involved in cell volume homeostasis; inorganic ion homeostasis; and inorganic ion transmembrane transport. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | SLC12A9 |
| Official Name | solute carrier family 12 member 9 [Source:HGNC Symbol;Acc:HGNC:17435] |
| Ensembl ID | ENSG00000146828 |
| Bio databases IDs | |
| Aliases | solute carrier family 12 member 9, cation-chloride cotransporter-interacting protein |
| Synonyms | CCC6, CIP1, hCCC6, LOC107986830, LOC107986831, solute carrier family 12 member 9, solute carrier family 12, member 9, solute carrier family 12 (potassium/chloride transporters), member 9, WO3.3 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SLC12A9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- cation:chloride symporter
- amino acid permease
- transporter
- K-Cl cotransporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SLC12A9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- potassium ion transmembrane transport
- chloride ion homeostasis
- potassium ion homeostasis
- cell volume homeostasis
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- potassium:chloride symporter activity
- cation:chloride symporter activity