PLPP5 Gene Summary [Human]
Enables diacylglycerol diphosphate phosphatase activity and phosphatidate phosphatase activity. Involved in phospholipid dephosphorylation. Predicted to be located in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | PLPP5 |
| Official Name | phospholipid phosphatase 5 [Source:HGNC Symbol;Acc:HGNC:25026] |
| Ensembl ID | ENSG00000147535 |
| Bio databases IDs | |
| Aliases | phospholipid phosphatase 5, diacylglycerol pyrophosphate phosphatase-like 1 |
| Synonyms | 1810019D05Rik, 2310022A04Rik, DPPL1, HTPAP, LOC683534, phospholipid phosphatase 5, Ppapdc1, PPAPDC1B |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PLPP5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- diacylglycerol pyrophosphate phosphatase
- Acid phosphatase homologues
- PAP2 superfamily
- phosphatidate phosphatase
- enzyme
- protein binding
- PAP2_like
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PLPP5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- phospholipid dephosphorylation
- phospholipid metabolic process
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- phosphatidate phosphatase activity
- protein binding
- diacylglycerol diphosphate phosphatase activity