TATDN1 Gene Summary [Human]

Predicted to enable 3'-5'-exodeoxyribonuclease activity. Predicted to be involved in DNA metabolic process and nucleic acid phosphodiester bond hydrolysis. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Nonsense Mediated Decay
Official Symbol
TATDN1
Official Name
TatD DNase domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24220]
Ensembl ID
ENSG00000147687
Bio databases IDs NCBI: 83940 Ensembl: ENSG00000147687
Aliases TatD DNase domain containing 1
Synonyms 2310079P03Rik, CDA11, LOC690068, TatD DNase domain containing 1
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TATDN1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • TatD related DNase
  • hydrolase, TatD family
  • protein binding
  • metallo-dependent_hydrolases

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • asthma
  • productive infection by HIV-1
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • Mitochondria
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human TATDN1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • DNA metabolic process

Cellular Component

Where in the cell the gene product is active
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • metal ion binding
  • 3'-5'-exodeoxyribonuclease activity

Gene-Specific Assays for Results You Can Trust

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