PABPC3 Gene Summary [Human]
Messenger RNA stability and translation initiation are extensively under the control of poly(A)-binding proteins (PABP). See PABPC1 (MIM 604679) for background information.[supplied by OMIM, Jul 2002]
Details
| Type | Protein Coding |
| Official Symbol | PABPC3 |
| Official Name | poly(A) binding protein cytoplasmic 3 [Source:HGNC Symbol;Acc:HGNC:8556] |
| Ensembl ID | ENSG00000151846 |
| Bio databases IDs | |
| Aliases | poly(A) binding protein cytoplasmic 3, testis PABP |
| Synonyms | PABP3, PABPL3, poly(A) binding protein cytoplasmic 3, tPABP |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PABPC3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ELAV/HuD family splicing factor
- polyadenylate binding protein, human types 1, 2, 3, 4 family
- RNA recognition motif (RRM) superfamily
- RNA recognition motif
- poly(A) binding protein
- protein binding
- poly-U binding splicing factor, half-pint family
- Poly-adenylate binding protein, unique domain
- C-terminal domain of Poly(A)-binding protein
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PABPC3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mRNA metabolic process
Cellular Component
Where in the cell the gene product is active
- nucleus
- extracellular vesicular exosome
- cytoplasmic stress granule
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding
- poly(A) RNA binding
- poly(U) RNA binding
- mRNA 3'-UTR binding