FRMD1 Gene Summary [Human]
Predicted to be involved in positive regulation of hippo signaling. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasmic side of apical plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | FRMD1 |
| Official Name | FERM domain containing 1 [Source:HGNC Symbol;Acc:HGNC:21240] |
| Ensembl ID | ENSG00000153303 |
| Bio databases IDs | |
| Aliases | FERM domain containing 1 |
| Synonyms | bA164L23.1, FERM domain containing 1 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human FRMD1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- FERM central domain
- Band 4.1 homologues
- Ubl1_cv_Nsp3_N-like
- protein binding
- Pleckstrin homology-like domain
- FERM domain B-lobe
- FERM C-terminal PH-like domain
- FERM N-terminal domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human FRMD1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of hippo signaling cascade
Cellular Component
Where in the cell the gene product is active
- cytoskeleton
Molecular Function
What the gene product does at the molecular level
- protein binding