LHFPL4 Gene Summary [Human]
This gene is a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. Mutations in one LHFP-like gene result in deafness in humans and mice, and a second LHFP-like gene is fused to a high-mobility group gene in a translocation-associated lipoma. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | LHFPL4 |
| Official Name | LHFPL tetraspan subfamily member 4 [Source:HGNC Symbol;Acc:HGNC:29568] |
| Ensembl ID | ENSG00000156959 |
| Bio databases IDs | |
| Aliases | LHFPL tetraspan subfamily member 4, GABAA receptor regulatory Lhfpl4 |
| Synonyms | 1190004M23RIK, B230384L07, GARLH4, LHFPL tetraspan subfamily member 4, lipoma HMGIC fusion partner-like protein 4, mKIAA4027 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human LHFPL4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- receptor binding
- Lipoma HMGIC fusion partner-like protein
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- organelle
- postsynaptic membrane
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human LHFPL4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sensory perception of sound
- gamma-aminobutyric acid receptor clustering
Cellular Component
Where in the cell the gene product is active
- inhibitory synapse
- dendrite
- postsynaptic membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- GABA receptor binding