RABIF Gene Summary [Human]
This gene encodes a member of the SCE4/YPT1/RAB family of small GTP-binding proteins that are involved in the regulation of intracellular vesicular transport. This protein stimulates GTP-GDP exchange in SEC4, and to a lesser extent in YPT1 and RAB3A, and may play a general role in vesicular transport. [provided by RefSeq, Oct 2011]
Details
| Type | Protein Coding |
| Official Symbol | RABIF |
| Official Name | RAB interacting factor [Source:HGNC Symbol;Acc:HGNC:9797] |
| Ensembl ID | ENSG00000183155 |
| Bio databases IDs | |
| Aliases | RAB interacting factor |
| Synonyms | E130318E12RIK, MSS4, RAB interacting factor, RASGFR3, RASGRF3, RGD1563962, Similar to mss4 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RABIF often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- zinc ion binding
- guanyl-nucleotide exchange factor
- protein binding
- transporter
- RabGEF
Pathways
Biological processes and signaling networks where the RABIF gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
role in cell
- exocytosis by
- degradation in
- fusion
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RABIF gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- membrane fusion
- small GTPase mediated signal transduction
- protein transport
- post-Golgi vesicle-mediated transport
Cellular Component
Where in the cell the gene product is active
- membrane
- cytosol
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- protein binding
- guanyl-nucleotide exchange factor activity