Lhfpl4 Gene Summary [Mouse]
Enables GABA receptor binding activity. Involved in gamma-aminobutyric acid receptor clustering; neurotransmitter receptor localization to postsynaptic specialization membrane; and regulation of inhibitory synapse assembly. Located in inhibitory synapse and postsynaptic membrane. Is active in GABA-ergic synapse and postsynaptic specialization. Is expressed in brain; heart; intestine; lung; and reproductive system. Orthologous to human LHFPL4 (LHFPL tetraspan subfamily member 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Lhfpl4 |
| Official Name | lipoma HMGIC fusion partner-like protein 4 [Source:MGI Symbol;Acc:MGI:3057108] |
| Ensembl ID | ENSMUSG00000042873 |
| Bio databases IDs | |
| Aliases | lipoma HMGIC fusion partner-like protein 4 |
| Synonyms | 1190004M23RIK, B230384L07, GARLH4, LHFPL tetraspan subfamily member 4, lipoma HMGIC fusion partner-like protein 4, mKIAA4027 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Lhfpl4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- receptor binding
- Lipoma HMGIC fusion partner-like protein
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- organelle
- postsynaptic membrane
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Lhfpl4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sensory perception of sound
- gamma-aminobutyric acid receptor clustering
Cellular Component
Where in the cell the gene product is active
- inhibitory synapse
- dendrite
- postsynaptic membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- GABA receptor binding