TGM7 Gene Summary [Human]
Transglutaminases (TGM; EC 2.3.2.13) are a family of structurally and functionally related enzymes that stabilize protein assemblies through the formation of gamma-glutamyl-epsilon lysine crosslinks. For additional background information on transglutaminases, see TGM1 (MIM 190195).[supplied by OMIM, Jul 2002]
Details
| Type | Protein Coding |
| Official Symbol | TGM7 |
| Official Name | transglutaminase 7 [Source:HGNC Symbol;Acc:HGNC:30790] |
| Ensembl ID | ENSG00000159495 |
| Bio databases IDs | |
| Aliases | transglutaminase 7, transglutaminase Z |
| Synonyms | LOC102552199, TGMZ, TGZ, transglutaminase 7 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TGM7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Transglutaminase-like superfamily
- Transglutaminase/protease-like homologues
- enzyme
- protein binding
- Transglutaminase family, C-terminal ig like domain
- Transglutaminase family
Pathways
Biological processes and signaling networks where the TGM7 gene in human plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TGM7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- peptide cross-linking
Molecular Function
What the gene product does at the molecular level
- protein-glutamine gamma-glutamyltransferase activity
- protein binding
- metal ion binding