UNKL Gene Summary [Human]
This gene encodes a RING finger protein that may function in Rac signaling. It can bind to Brg/Brm-associated factor 60b and can promote its ubiquitination. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Details
| Type | Protein Coding |
| Official Symbol | UNKL |
| Official Name | unk like zinc finger [Source:HGNC Symbol;Acc:HGNC:14184] |
| Ensembl ID | ENSG00000059145 |
| Bio databases IDs | |
| Aliases | unk like zinc finger |
| Synonyms | 1300004G08Rik, AU067667, C16orf28, FLJ23360, RGD1565247, unkempt family like zinc finger, unk like zinc finger, ZC3H5L, ZC3HDC5L |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human UNKL often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ezrin/radixin/moesin, alpha-helical domain
- Unkempt Zinc finger domain 1 (Znf1)
- RING finger (Really Interesting New Gene) domain and U-box domain superfamily
- enzyme
- Zinc finger C-x8-C-x5-C-x3-H type (and similar)
- protein binding
- Zinc finger, C3HC4 type (RING finger)
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human UNKL gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein ubiquitination
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding
- transferase activity