CCDC28B Gene Summary [Human]
The product of this gene localizes to centrosomes and basal bodies. The protein colocalizes with several proteins associated with Bardet-Biedl syndrome (BBS) and participates in the regulation of cilia development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Details
| Type | Protein Coding |
| Official Symbol | CCDC28B |
| Official Name | coiled-coil domain containing 28B [Source:HGNC Symbol;Acc:HGNC:28163] |
| Ensembl ID | ENSG00000160050 |
| Bio databases IDs | |
| Aliases | coiled-coil domain containing 28B |
| Synonyms | 1110002E08Rik, 1810010N17Rik, coiled-coil domain containing 28B, MGC1203 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CCDC28B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Coiled-coil domain-containing protein 28
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- centrosome
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CCDC28B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cilium morphogenesis
Cellular Component
Where in the cell the gene product is active
- centrosome
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding