DMKN Gene Summary [Human]
This gene is upregulated in inflammatory diseases, and it was first observed as expressed in the differentiated layers of skin. The most interesting aspect of this gene is the differential use of promoters and terminators to generate isoforms with unique cellular distributions and domain components. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2010]
Details
| Type | Retained Intron |
| Official Symbol | DMKN |
| Official Name | dermokine [Source:HGNC Symbol;Acc:HGNC:25063] |
| Ensembl ID | ENSG00000161249 |
| Bio databases IDs | |
| Aliases | dermokine |
| Synonyms | 1110014F24RIK, AW561900, C130074A08, cI-36, dermokine, LOC100912070, RGD1561521, SK30, SK89, UNQ729, ZD52F10 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DMKN often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- dermokine
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human DMKN gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular space
Molecular Function
What the gene product does at the molecular level
- protein binding