ZG16B Gene Summary [Human]
Predicted to enable carbohydrate binding activity. Involved in retina homeostasis. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ZG16B |
| Official Name | zymogen granule protein 16B [Source:HGNC Symbol;Acc:HGNC:30456] |
| Ensembl ID | ENSG00000162078 |
| Bio databases IDs | |
| Aliases | zymogen granule protein 16B, jacalin-like lectin domain containing 2 |
| Synonyms | EECP, HRPE773, JCLN2, LOC124220, PAUF, PRO1567, RGD1562673, Sbpl, zymogen granule protein 16B |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZG16B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Jacalin-like lectin domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- pancreatic neoplasia
- vascular leak syndrome
role in cell
- expression in
- proliferation
- activation in
- migration
- binding in
- tubulation
- Clathrin mediated endocytosis by
- disruption
- disruption in
- permeability
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- apicolateral membrane
- Extracellular Space
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ZG16B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell migration
Cellular Component
Where in the cell the gene product is active
- apicolateral plasma membrane
- extracellular space
- extracellular vesicular exosome
- cytoplasm
- extracellular region
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- carbohydrate binding