TYW5 Gene Summary [Human]
Enables several functions, including iron ion binding activity; protein homodimerization activity; and tRNAPhe (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity. Involved in wybutosine biosynthetic process. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | TYW5 |
| Official Name | tRNA-yW synthesizing protein 5 [Source:HGNC Symbol;Acc:HGNC:26754] |
| Ensembl ID | ENSG00000162971 |
| Bio databases IDs | |
| Aliases | tRNA-yW synthesizing protein 5 |
| Synonyms | 1110034B05Rik, C2orf60, hTYW5, RGD1311269, tRNA-yW synthesizing protein 5 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TYW5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- tRNA binding
- 2-oxoglutarate:oxygen oxidoreductase
- protein homodimerization
- iron ion binding
- enzyme
- protein binding
- Cupin-like domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TYW5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- wybutosine biosynthetic process
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein homodimerization activity
- iron ion binding
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
- tRNA binding