SAP30BP Gene Summary [Human]

Involved in modulation by host of symbiont transcription; positive regulation of histone deacetylation; and response to virus. Located in intermediate filament cytoskeleton and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Nonsense Mediated Decay
Official Symbol
SAP30BP
Official Name
SAP30 binding protein [Source:HGNC Symbol;Acc:HGNC:30785]
Ensembl ID
ENSG00000161526
Bio databases IDs NCBI: 29115 Ensembl: ENSG00000161526
Aliases SAP30 binding protein
Synonyms 2700016D05Rik, HCNGP, HTRG, HTRP, RGD1565537, SAP30 binding protein
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SAP30BP often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • transcription regulator
  • HCNGP-like protein
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • paralysis
  • schizophrenia
  • rotator cuff tear
  • infection by HIV-1
regulated by
role in cell
  • phosphorylation in
  • binding in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • intermediate filament cytoskeleton
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human SAP30BP gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • modulation by host of symbiont transcription
  • regulation of transcription, DNA-dependent
  • response to virus

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • intermediate filament cytoskeleton
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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