METTL6 Gene Summary [Human]
Enables enzyme binding activity. Involved in tRNA methylation. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | METTL6 |
| Official Name | methyltransferase like 6 [Source:HGNC Symbol;Acc:HGNC:28343] |
| Ensembl ID | ENSG00000206562 |
| Bio databases IDs | |
| Aliases | methyltransferase like 6, methyltransferase 6, methylcytidine |
| Synonyms | 1600013P15Rik, hMETTL6, methyltransferase 6, methylcytidine, methyltransferase 6, tRNA N3-cytidine |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human METTL6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- enzyme binding
- enzyme
- protein binding
- tRNA (cytosine)-methyltransferase
- AdoMet_MTases
- methyltransferase domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human METTL6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- tRNA methylation
- tRNA modification
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- tRNA (cytosine-3-)-methyltransferase activity
- enzyme binding