CDC20B Gene Summary [Human]

Predicted to enable anaphase-promoting complex binding activity and ubiquitin ligase activator activity. Predicted to be involved in anaphase-promoting complex-dependent catabolic process and positive regulation of anaphase-promoting complex-dependent catabolic process. Predicted to be part of anaphase-promoting complex. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
CDC20B
Official Name
cell division cycle 20B [Source:HGNC Symbol;Acc:HGNC:24222]
Ensembl ID
ENSG00000164287
Bio databases IDs NCBI: 166979 Ensembl: ENSG00000164287
Aliases cell division cycle 20B
Synonyms cell division cycle 20B, EG238896, EG622422, G6VTS76519
Species
Human, Homo sapiens
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CDC20B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • WD40 repeats
  • WD domain, G-beta repeat
  • WD40
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • breast cancer
  • diabetic nephropathy
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • organelle

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human CDC20B gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • anaphase-promoting complex

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • anaphase-promoting complex binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.