TMEM184A Gene Summary [Human]

Predicted to enable heparin binding activity. Predicted to act upstream of or within germ-line sex determination; regulation of protein localization; and regulation of secretion. Predicted to be located in cytoplasmic vesicle; perinuclear region of cytoplasm; and plasma membrane. Predicted to be active in early endosome membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
TMEM184A
Official Name
transmembrane protein 184A [Source:HGNC Symbol;Acc:HGNC:28797]
Ensembl ID
ENSG00000164855
Bio databases IDs NCBI: 202915 Ensembl: ENSG00000164855
Aliases transmembrane protein 184A, sexually dimorphic, expressed in male gonads 1
Synonyms LOC101927064, RGD1306702, SDMG1, SLC51C1, transmembrane protein 184A
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TMEM184A often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • heparin binding
  • Organic solute transporter Ostalpha

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Alzheimer disease
regulated by
regulates
role in cell
  • expression in
  • phosphorylation in
  • proliferation
  • formation
  • sex determination
  • formation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytoplasmic vesicle membrane
  • perinuclear region
  • Plasma Membrane
  • endosomes
  • secretory granule membrane
  • endosomal membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human TMEM184A gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • transport

Cellular Component

Where in the cell the gene product is active
  • early endosome membrane
  • secretory granule membrane
  • cytoplasmic vesicle membrane
  • perinuclear region of cytoplasm
  • transport vesicle membrane
  • endosome
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • heparin binding
  • transporter activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.