Tmem184a Gene Summary [Mouse]
Predicted to enable heparin binding activity and transmembrane transporter activity. Acts upstream of or within germ-line sex determination; regulation of protein localization; and regulation of secretion. Located in early endosome membrane and secretory granule membrane. Is expressed in several structures, including exocrine gland; gonad; gut; lung; and nose. Orthologous to human TMEM184A (transmembrane protein 184A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmem184a |
| Official Name | transmembrane protein 184a [Source:MGI Symbol;Acc:MGI:2385897] |
| Ensembl ID | ENSMUSG00000036687 |
| Bio databases IDs | |
| Aliases | transmembrane protein 184a |
| Synonyms | LOC101927064, RGD1306702, SDMG1, SLC51C1, transmembrane protein 184A |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmem184a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- heparin binding
- Organic solute transporter Ostalpha
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytoplasmic vesicle membrane
- perinuclear region
- Plasma Membrane
- endosomes
- secretory granule membrane
- endosomal membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmem184a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- transport
Cellular Component
Where in the cell the gene product is active
- early endosome membrane
- secretory granule membrane
- cytoplasmic vesicle membrane
- perinuclear region of cytoplasm
- transport vesicle membrane
- endosome
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- heparin binding
- transporter activity