STK32C Gene Summary [Human]
The protein encoded by this gene is a member of the serine/threonine protein kinase family. It is thought that this family member is functional in brain due to its high expression levels there. DNA methylation differences have been found in this gene in monozygotic twins that are discordant for adolescent depression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Details
| Type | Processed Transcript |
| Official Symbol | STK32C |
| Official Name | serine/threonine kinase 32C [Source:HGNC Symbol;Acc:HGNC:21332] |
| Ensembl ID | ENSG00000165752 |
| Bio databases IDs | |
| Aliases | serine/threonine kinase 32C |
| Synonyms | LOC102724967, PKE, Pkek, serine/threonine kinase 32C, YANK3 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human STK32C often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- Serine/Threonine protein kinases, catalytic domain
- Protein kinase (unclassified specificity)
- Protein Kinases, catalytic domain
- Protein tyrosine and serine/threonine kinase
- protein binding
- Protein kinase domain
- Tyrosine kinase, catalytic domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- acute myeloid leukemia
- idiopathic scoliosis
- spontaneous preterm birth
- attention deficit hyperactivity disorder
- systemic lupus erythematosus nephritis
- ocular sarcoidosis
- ophthalmic disorder
- pneumococcal meningitis
- bronchopulmonary dysplasia
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human STK32C gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- peptidyl-serine phosphorylation
- intracellular signal transduction
Molecular Function
What the gene product does at the molecular level
- ATP binding
- protein binding
- metal ion binding
- protein serine/threonine kinase activity