CIAO2B Gene Summary [Human]
Involved in chromosome segregation; iron-sulfur cluster assembly; and protein maturation by iron-sulfur cluster transfer. Located in cytosol; nucleoplasm; and spindle. Part of CIA complex and MMXD complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | CIAO2B |
| Official Name | cytosolic iron-sulfur assembly component 2B [Source:HGNC Symbol;Acc:HGNC:24261] |
| Ensembl ID | ENSG00000166595 |
| Bio databases IDs | |
| Aliases | cytosolic iron-sulfur assembly component 2B |
| Synonyms | 1110019N10Rik, CGI-128, CIA2B, cytosolic iron-sulfur assembly component 2B, cytosolic iron-sulphur assembly component 2B, FAM96B, LOC679251, MIP18, RGD1311762 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CIAO2B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Iron-sulfur cluster assembly protein
- protein binding
Pathways
Biological processes and signaling networks where the CIAO2B gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- spindle apparatus
- Nucleus
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CIAO2B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- chromosome segregation
- iron-sulfur cluster assembly
Cellular Component
Where in the cell the gene product is active
- MMXD complex
- nucleus
- cytoplasm
- spindle
- cytosol
- midbody
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding