Ciao2b Gene Summary [Mouse]

Predicted to be involved in chromosome segregation; iron-sulfur cluster assembly; and protein maturation. Predicted to be located in cytosol; nucleoplasm; and spindle. Predicted to be part of MMXD complex and cytosolic [4Fe-4S] assembly targeting complex. Orthologous to human CIAO2B (cytosolic iron-sulfur assembly component 2B). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Ciao2b
Official Name
cytosolic iron-sulfur assembly component 2B [Source:MGI Symbol;Acc:MGI:1915773]
Ensembl ID
ENSMUSG00000031879
Bio databases IDs NCBI: 68523 Ensembl: ENSMUSG00000031879
Aliases cytosolic iron-sulfur assembly component 2B
Synonyms 1110019N10Rik, CGI-128, CIA2B, cytosolic iron-sulfur assembly component 2B, cytosolic iron-sulphur assembly component 2B, FAM96B, LOC679251, MIP18, RGD1311762
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ciao2b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Iron-sulfur cluster assembly protein
  • protein binding

Pathways

Biological processes and signaling networks where the Ciao2b gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • ductal breast carcinoma
  • ductal breast cancer
regulated by
role in cell
  • frequency
  • downregulation in
  • segregation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • spindle apparatus
  • Nucleus
  • cytosol
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ciao2b gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • chromosome segregation
  • iron-sulfur cluster assembly

Cellular Component

Where in the cell the gene product is active
  • MMXD complex
  • nucleus
  • cytoplasm
  • spindle
  • cytosol
  • midbody
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.