VWCE Gene Summary [Human]

Predicted to enable calcium ion binding activity. Involved in cellular response to virus. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Nonsense Mediated Decay
Official Symbol
VWCE
Official Name
von Willebrand factor C and EGF domains [Source:HGNC Symbol;Acc:HGNC:26487]
Ensembl ID
ENSG00000167992
Bio databases IDs NCBI: 220001 Ensembl: ENSG00000167992
Aliases von Willebrand factor C and EGF domains
Synonyms 1300015B04Rik, LOC100911250, LOC102553236, RGD1309910, URG11, von Willebrand factor C and EGF domains, VWC1
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human VWCE often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Complement Clr-like EGF-like
  • von Willebrand factor type C domain
  • protein binding
  • Coagulation Factor Xa inhibitory site
  • EGF_CA

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • neoplasia
  • epithelial cancer
  • androgenic alopecia
  • prostatic adenocarcinoma
  • prostate cancer
regulated by
regulates
role in cell
  • colony formation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human VWCE gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • extracellular region

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • calcium ion binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.