Vwce Gene Summary [Rat]

Predicted to enable calcium ion binding activity. Predicted to be involved in cellular response to virus. Predicted to be located in extracellular region. Predicted to be active in cytoplasm. Orthologous to human VWCE (von Willebrand factor C and EGF domains). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Vwce
Official Name
von Willebrand factor C and EGF domains [Source:RGD Symbol;Acc:1309910]
Ensembl ID
ENSRNOG00000060269
Bio databases IDs NCBI: 309209 Ensembl: ENSRNOG00000060269
Aliases von Willebrand factor C and EGF domains
Synonyms 1300015B04Rik, LOC100911250, LOC102553236, RGD1309910, URG11, von Willebrand factor C and EGF domains, VWC1
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Vwce often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Complement Clr-like EGF-like
  • von Willebrand factor type C domain
  • protein binding
  • Coagulation Factor Xa inhibitory site
  • EGF_CA

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • neoplasia
  • epithelial cancer
  • androgenic alopecia
  • prostatic adenocarcinoma
  • prostate cancer
regulated by
regulates
role in cell
  • colony formation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Vwce gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • extracellular region

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • calcium ion binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.