DDX19A Gene Summary [Human]

Predicted to enable RNA binding activity and RNA helicase activity. Predicted to be involved in poly(A)+ mRNA export from nucleus. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Processed Transcript
Official Symbol
DDX19A
Official Name
DEAD-box helicase 19A [Source:HGNC Symbol;Acc:HGNC:25628]
Ensembl ID
ENSG00000168872
Bio databases IDs NCBI: 55308 Ensembl: ENSG00000168872
Aliases DEAD-box helicase 19A
Synonyms Ddx19, DDX19-DDX19L, DDX19L, DEAD-box helicase 19A, FLJ11126, Zd10A, ZD10B
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DDX19A often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • helicase superfamily c-terminal domain
  • DEAD/DEAH box helicase
  • N-terminal helicase domain of the DEAD-box helicase superfamily
  • enzyme
  • protein binding
  • DEAD-like helicases superfamily
  • Helicase conserved C-terminal domain
  • P-loop containing Nucleoside Triphosphate Hydrolases

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • zinc gluconate
  • CD3 (complex)
  • NEF
role in cell
  • apoptosis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • nuclear pores

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human DDX19A gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • response to zinc ion
  • positive regulation of apoptotic process
  • poly(A)+ mRNA export from nucleus

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasmic stress granule
  • membrane
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • ATPase activity
  • ATP binding
  • protein binding
  • RNA helicase activity
  • mRNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.