SHE Gene Summary [Human]
Predicted to enable phosphotyrosine residue binding activity. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | SHE |
| Official Name | Src homology 2 domain containing E [Source:HGNC Symbol;Acc:HGNC:27004] |
| Ensembl ID | ENSG00000169291 |
| Bio databases IDs | |
| Aliases | Src homology 2 domain containing E |
| Synonyms | 9430022A14, LOC126669, LOC686570, RGD1563897, Src homology 2 domain containing E, src homology 2 domain-containing transforming protein E |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SHE often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Src homology 2 (SH2) domain
- protein binding
Pathways
Biological processes and signaling networks where the SHE gene in human plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SHE gene, providing context for its role in the cell.
Molecular Function
What the gene product does at the molecular level
- phosphotyrosine binding
- protein binding