She Gene Summary [Mouse]
Predicted to enable phosphotyrosine residue binding activity. Is expressed in embryo mesenchyme; endocardial lining; heart trabecula; and heart valve. Orthologous to human SHE (Src homology 2 domain containing E). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | She |
| Official Name | src homology 2 domain-containing transforming protein E [Source:MGI Symbol;Acc:MGI:1099462] |
| Ensembl ID | ENSMUSG00000046280 |
| Bio databases IDs | |
| Aliases | src homology 2 domain-containing transforming protein E |
| Synonyms | 9430022A14, LOC126669, LOC686570, RGD1563897, Src homology 2 domain containing E, src homology 2 domain-containing transforming protein E |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse She often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Src homology 2 (SH2) domain
- protein binding
Pathways
Biological processes and signaling networks where the She gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse She gene, providing context for its role in the cell.
Molecular Function
What the gene product does at the molecular level
- phosphotyrosine binding
- protein binding