RAMAC Gene Summary [Human]
Enables RNA binding activity and enzyme activator activity. Involved in methylation and recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex. Located in nucleoplasm. Part of mRNA cap binding activity complex and mRNA cap methyltransferase complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | RAMAC |
| Official Name | RNA guanine-7 methyltransferase activating subunit [Source:HGNC Symbol;Acc:HGNC:31022] |
| Ensembl ID | ENSG00000169612 |
| Bio databases IDs | |
| Aliases | RNA guanine-7 methyltransferase activating subunit, RNMT-activating mini protein |
| Synonyms | 2410047I02Rik, 2610204K14Rik, C15orf18, FAM103A1, HsT19360, RAM, RAMMET, RGD1310022, RNA guanine-7 methyltransferase activating subunit |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RAMAC often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- mRNA cap methylation, RNMT-activating mini protein
- protein binding
- enzyme activator activity
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RAMAC gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mRNA capping
- methylation
Cellular Component
Where in the cell the gene product is active
- nucleus
- mRNA cap methyltransferase complex
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- enzyme activator activity