MT1B Gene Summary [Human]

The protein encoded by this gene binds heavy metals and protects against toxicity from heavy metal ions. This gene is found in a cluster of similar genes on chromosome 16. [provided by RefSeq, Jul 2016]

Details

Type
Protein Coding
Official Symbol
MT1B
Official Name
metallothionein 1B [Source:HGNC Symbol;Acc:HGNC:7394]
Ensembl ID
ENSG00000169688
Bio databases IDs NCBI: 4490 Ensembl: ENSG00000169688
Aliases metallothionein 1B
Synonyms metallothionein 1B, MT1, MT1Q, MT-IB, MTP
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MT1B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • zinc ion binding
  • Metallothionein
  • protein binding

Pathways

Biological processes and signaling networks where the MT1B gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • colon cancer
  • nonalcoholic steatohepatitis
regulated by
regulates
role in cell
  • expression in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Nucleus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human MT1B gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • negative regulation of growth
  • detoxification of copper ion
  • cellular response to zinc ion
  • cellular response to cadmium ion
  • cellular zinc ion homeostasis
  • cellular response to copper ion

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • zinc ion binding
  • protein binding
  • metal ion binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.