PWWP2A Gene Summary [Human]
Enables chromatin binding activity and histone binding activity. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | PWWP2A |
| Official Name | PWWP domain containing 2A [Source:HGNC Symbol;Acc:HGNC:29406] |
| Ensembl ID | ENSG00000170234 |
| Bio databases IDs | |
| Aliases | PWWP domain containing 2A |
| Synonyms | 4631424J17Rik, AK039984, D930040F23Rik, KIAA1935, LOC683932, MST101, PWWP domain containing 2A, RGD1305891 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PWWP2A often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- histone binding
- binding protein
- protein binding activity, bridging
- PWWP domain
- PWWP (Pro-Trp-Trp-Pro) domain
- chromatin binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PWWP2A gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of transcription elongation from RNA polymerase II promoter
- regulation of transcriptional start site selection at RNA polymerase II promoter
- chromatin remodeling
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- protein binding
- histone binding
- methylated histone residue binding
- chromatin binding