ELP5 Gene Summary [Human]
Predicted to contribute to tRNA binding activity. Predicted to be involved in positive regulation of cell migration and tRNA modification. Located in cytosol and nucleoplasm. Part of elongator holoenzyme complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ELP5 |
| Official Name | elongator acetyltransferase complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:30617] |
| Ensembl ID | ENSG00000170291 |
| Bio databases IDs | |
| Aliases | elongator acetyltransferase complex subunit 5, dermal papilla derived protein 6, S-phase 2 protein |
| Synonyms | C17orf81, DERP6, elongator acetyltransferase complex subunit 5, HSPC002, MST071, MSTP071, Rai12 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ELP5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Elongator subunit Iki1
- protein binding
- P-loop containing Nucleoside Triphosphate Hydrolases
Pathways
Biological processes and signaling networks where the ELP5 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ELP5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of translation
- tRNA wobble uridine modification
- tRNA modification
- positive regulation of cell migration
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- Elongator holoenzyme complex
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- tRNA binding