ATXN1L Gene Summary [Human]
Predicted to enable DNA binding activity and RNA binding activity. Predicted to be involved in several processes, including learning or memory; regulation of transcription, DNA-templated; and social behavior. Predicted to act upstream of or within several processes, including lung alveolus development; negative regulation of transcription by RNA polymerase II; and positive regulation of hematopoietic stem cell proliferation. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ATXN1L |
| Official Name | ataxin 1 like [Source:HGNC Symbol;Acc:HGNC:33279] |
| Ensembl ID | ENSG00000224470 |
| Bio databases IDs | |
| Aliases | ataxin 1 like, brother of ataxin 1 |
| Synonyms | ataxin 1-like, AW558552, BOAT, BOAT1, C330011L24Rik, D6Mgi37, D8Ertd587e, LOC100131476, RGD1561758 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ATXN1L often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ataxin-1 and HBP1 module (AXH)
- protein domain specific binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ATXN1L gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- social behavior
- negative regulation of transcription from RNA polymerase II promoter
- lung alveolus development
- extracellular matrix organization
- anatomical structure development
- regulation of transcription, DNA-dependent
- transcription from RNA polymerase II promoter
- brain development
- learning
- memory
Cellular Component
Where in the cell the gene product is active
- dendrite
- nucleus
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- POZ domain binding
- DNA binding
- protein binding
- RNA binding