EMB Gene Summary [Human]

This gene encodes a transmembrane glycoprotein that is a member of the immunoglobulin superfamily. The encoded protein may be involved in cell growth and development by mediating interactions between the cell and extracellular matrix. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Jan 2009]

Details

Type
Protein Coding
Official Symbol
EMB
Official Name
embigin [Source:HGNC Symbol;Acc:HGNC:30465]
Ensembl ID
ENSG00000170571
Bio databases IDs NCBI: 133418 Ensembl: ENSG00000170571
Aliases embigin
Synonyms embigin, GP70
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human EMB often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • immunoglobulin domain
  • Immunoglobulin like
  • intracellular domain
  • Immunoglobulin I-set domain
  • protein binding
  • phosphorylation site

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • plasma cell neoplasm
  • B cell cancer
  • mature B-cell neoplasia
  • early onset hypertension
  • non-insulin-dependent diabetes mellitus
regulated by
regulates
  • nicotinic acetylcholine receptor
  • taurine
role in cell
  • morphology
  • adhesion
  • sprouting
  • clustering in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane
  • neuromuscular junctions

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human EMB gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • dendrite self-avoidance
  • axon guidance
  • plasma membrane lactate transport
  • homophilic cell adhesion

Cellular Component

Where in the cell the gene product is active
  • synapse
  • axon
  • plasma membrane

Gene-Specific Assays for Results You Can Trust

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