Emb Gene Summary [Mouse]
Predicted to enable cell-cell adhesion mediator activity. Predicted to be involved in homophilic cell adhesion via plasma membrane adhesion molecules; neuron development; and plasma membrane lactate transport. Predicted to be located in synapse. Predicted to be active in axon and plasma membrane. Is expressed in several structures, including alimentary system; ectoderm; egg cylinder; genitourinary system; and nervous system. Orthologous to human EMB (embigin). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Emb |
| Official Name | embigin [Source:MGI Symbol;Acc:MGI:95321] |
| Ensembl ID | ENSMUSG00000021728 |
| Bio databases IDs | |
| Aliases | embigin |
| Synonyms | embigin, GP70 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Emb often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- immunoglobulin domain
- Immunoglobulin like
- intracellular domain
- Immunoglobulin I-set domain
- protein binding
- phosphorylation site
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- plasma cell neoplasm
- B cell cancer
- mature B-cell neoplasia
- early onset hypertension
- non-insulin-dependent diabetes mellitus
regulates
- nicotinic acetylcholine receptor
- taurine
role in cell
- morphology
- adhesion
- sprouting
- clustering in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- neuromuscular junctions
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Emb gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- dendrite self-avoidance
- axon guidance
- plasma membrane lactate transport
- homophilic cell adhesion
Cellular Component
Where in the cell the gene product is active
- synapse
- axon
- plasma membrane