GIMAP8 Gene Summary [Human]
This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | GIMAP8 |
| Official Name | GTPase, IMAP family member 8 [Source:HGNC Symbol;Acc:HGNC:21792] |
| Ensembl ID | ENSG00000171115 |
| Bio databases IDs | |
| Aliases | GTPase, IMAP family member 8, immune-associated nucleotide-binding protein 9 |
| Synonyms | Gm457, GTPase, IMAP family member 8, IAN6, IAN-9, IANT, IMAP8 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GIMAP8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- small GTP-binding protein domain
- 50S ribosome-binding GTPase
- P-loop containing Nucleoside Triphosphate Hydrolases
- AIG1 family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human GIMAP8 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of T cell apoptotic process
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- cytosol
- endoplasmic reticulum
- Golgi apparatus
Molecular Function
What the gene product does at the molecular level
- GTP binding