Gimap8 Gene Summary [Rat]
Predicted to enable GTP binding activity. Predicted to act upstream of or within regulation of T cell apoptotic process. Predicted to be located in Golgi apparatus; cytosol; and mitochondrion. Predicted to be active in endoplasmic reticulum. Orthologous to human GIMAP8 (GTPase, IMAP family member 8). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gimap8 |
| Official Name | GTPase, IMAP family member 8 [Source:RGD Symbol;Acc:1564570] |
| Ensembl ID | ENSRNOG00000020169 |
| Bio databases IDs | |
| Aliases | GTPase, IMAP family member 8 |
| Synonyms | Gm457, GTPase, IMAP family member 8, IAN6, IAN-9, IANT, IMAP8 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Gimap8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- small GTP-binding protein domain
- 50S ribosome-binding GTPase
- P-loop containing Nucleoside Triphosphate Hydrolases
- AIG1 family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Gimap8 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of T cell apoptotic process
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- cytosol
- endoplasmic reticulum
- Golgi apparatus
Molecular Function
What the gene product does at the molecular level
- GTP binding