SLC2A14 Gene Summary [Human]
Members of the glucose transporter (GLUT) family, including SLC2A14, are highly conserved integral membrane proteins that transport hexoses such as glucose and fructose into all mammalian cells. GLUTs show tissue and cell-type specific expression (Wu and Freeze, 2002 [PubMed 12504846]).[supplied by OMIM, Mar 2008]
Details
| Type | Protein Coding |
| Official Symbol | SLC2A14 |
| Official Name | solute carrier family 2 member 14 [Source:HGNC Symbol;Acc:HGNC:18301] |
| Ensembl ID | ENSG00000173262 |
| Bio databases IDs | |
| Aliases | solute carrier family 2 member 14 |
| Synonyms | GLUT14, SLC2A3P3, solute carrier family 2 member 14 |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SLC2A14 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- hexose transporter
- Sugar (and other) transporter
- MFS transporter, sugar porter (SP) family
- Major Facilitator Superfamily
- phosphate:H+ symporter
- organic anion transporter
- transporter
Pathways
Biological processes and signaling networks where the SLC2A14 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- aggresome
- cellular membrane
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SLC2A14 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- dehydroascorbic acid transport
- spermatogenesis
- cell differentiation
- glucose import
Cellular Component
Where in the cell the gene product is active
- nucleus
- aggresome
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- D-glucose transmembrane transporter activity
- dehydroascorbic acid transporter activity
- glucose transmembrane transporter activity