SMAP2 Gene Summary [Human]
Predicted to enable GTPase activator activity. Predicted to be involved in regulation of catalytic activity. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | SMAP2 |
| Official Name | small ArfGAP2 [Source:HGNC Symbol;Acc:HGNC:25082] |
| Ensembl ID | ENSG00000084070 |
| Bio databases IDs | |
| Aliases | small ArfGAP2 |
| Synonyms | 1810031K02Rik, LOC107984945, RGD1308418, small ArfGAP 2, SMAP1L |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SMAP2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Putative GTP-ase activating proteins for the small GTPase, ARF
- protein binding
- GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
- Putative GTPase activating protein for Arf
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
- trans Golgi network
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SMAP2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding
- GTPase activator activity