GOLT1A Gene Summary [Human]

Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Located in Golgi apparatus subcompartment; endoplasmic reticulum; and nuclear envelope. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
GOLT1A
Official Name
golgi transport 1A [Source:HGNC Symbol;Acc:HGNC:24766]
Ensembl ID
ENSG00000174567
Bio databases IDs NCBI: 127845 Ensembl: ENSG00000174567
Aliases golgi transport 1A
Synonyms 0610012C01Rik, CGI-141, golgi transport 1A, GOT1, GOT1B, hGOT1b, HMFN1187, Kiss1, metastatin, RGD1566310, YMR292W
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GOLT1A often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Got1/Sft2-like family
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • diabetic nephropathy
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Endoplasmic Reticulum
  • trans Golgi network
  • nuclear envelope
  • Golgi cisternae

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human GOLT1A gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • ER to Golgi vesicle-mediated transport
  • protein transport
  • retrograde transport, endosome to Golgi

Cellular Component

Where in the cell the gene product is active
  • nuclear envelope
  • trans-Golgi network
  • membrane
  • cytosol
  • endoplasmic reticulum
  • Golgi membrane
  • Golgi cis cisterna

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.