C3orf33 Gene Summary [Human]
Involved in negative regulation of ERK1 and ERK2 cascade and regulation of DNA-binding transcription factor activity. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | C3orf33 |
| Official Name | chromosome 3 open reading frame 33 [Source:HGNC Symbol;Acc:HGNC:26434] |
| Ensembl ID | ENSG00000174928 |
| Bio databases IDs | |
| Aliases | chromosome 3 open reading frame 33 |
| Synonyms | AC3-33, C2h3orf33, C3orf33l, chromosome 3 open reading frame 33, E130311K13Rik, RGD1565059, RIKEN cDNA E130311K13 gene, similar to human chromosome 3 open reading frame 33 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human C3orf33 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human C3orf33 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of ERK1 and ERK2 cascade
- regulation of sequence-specific DNA binding transcription factor activity
Cellular Component
Where in the cell the gene product is active
- extracellular space
- membrane
Molecular Function
What the gene product does at the molecular level
- protein binding