PDIK1L Gene Summary [Human]

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in meiotic cell cycle. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
PDIK1L
Official Name
PDLIM1 interacting kinase 1 like [Source:HGNC Symbol;Acc:HGNC:18981]
Ensembl ID
ENSG00000175087
Bio databases IDs NCBI: 149420 Ensembl: ENSG00000175087
Aliases PDLIM1 interacting kinase 1 like
Synonyms CLIK1L, LOC149420, PDLIM1 interacting kinase 1 like, RGD1307476, STK35L2
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PDIK1L often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • kinase
  • Serine/Threonine protein kinases, catalytic domain
  • protein serine/threonine kinase
  • Protein kinase (unclassified specificity)
  • Protein Kinases, catalytic domain
  • protein binding
  • Protein kinase domain
  • Tyrosine kinase, catalytic domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • non-insulin-dependent diabetes mellitus
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human PDIK1L gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of translational initiation by eIF2 alpha phosphorylation

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • ATP binding
  • protein binding
  • eukaryotic translation initiation factor 2alpha kinase activity

Gene-Specific Assays for Results You Can Trust

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