INHBC Gene Summary [Human]

This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of homodimeric and heterodimeric activin complexes. The heterodimeric complex may function in the inhibition of activin A signaling. Transgenic mice overexpressing this gene exhibit defects in testis, liver and prostate. [provided by RefSeq, Aug 2016]

Details

Type
Protein Coding
Official Symbol
INHBC
Official Name
inhibin subunit beta C [Source:HGNC Symbol;Acc:HGNC:6068]
Ensembl ID
ENSG00000175189
Bio databases IDs NCBI: 3626 Ensembl: ENSG00000175189
Aliases inhibin subunit beta C
Synonyms ACTIVIN beta C, ACTIVIN β C, IHBC, inhibin beta-C, inhibin subunit beta C, inhibin subunit β C, inhibin β-C, LNHBC
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human INHBC often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • transforming growth factor-beta receptor binding
  • TGF_beta_SF
  • Transforming growth factor beta like domain
  • growth factor

Pathways

Biological processes and signaling networks where the INHBC gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • gout
  • hypoalbuminemia
  • chronic kidney disease
  • coronary artery disease
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • plasma

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human INHBC gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • signal transduction

Cellular Component

Where in the cell the gene product is active
  • extracellular space
  • extracellular region

Molecular Function

What the gene product does at the molecular level
  • growth factor activity
  • transforming growth factor beta receptor binding
  • cytokine activity
  • hormone activity

Gene-Specific Assays for Results You Can Trust

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