TP53I11 Gene Summary [Human]
Predicted to be involved in negative regulation of cell population proliferation. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | TP53I11 |
| Official Name | tumor protein p53 inducible protein 11 [Source:HGNC Symbol;Acc:HGNC:16842] |
| Ensembl ID | ENSG00000175274 |
| Bio databases IDs | |
| Aliases | tumor protein p53 inducible protein 11 |
| Synonyms | PIG11, transformation related protein 53 inducible protein 11, Trp53i11, tumor protein p53 inducible protein 11, tumour protein p53 inducible protein 11 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TP53I11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Tumour protein p53-inducible protein 11
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- cervical small cell carcinoma
- extrapulmonary small cell cancer
- epithelial uterine cancer
- cervical cancer
role in cell
- proliferation
- lysis
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TP53I11 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of cell proliferation
Cellular Component
Where in the cell the gene product is active
- membrane