UNC119B Gene Summary [Human]
Enables lipid binding activity. Involved in cilium assembly and lipoprotein transport. Located in ciliary transition zone. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | UNC119B |
| Official Name | unc-119 lipid binding chaperone B [Source:HGNC Symbol;Acc:HGNC:16488] |
| Ensembl ID | ENSG00000175970 |
| Bio databases IDs | |
| Aliases | unc-119 lipid binding chaperone B, POC7 centriolar protein homolog B (Chlamydomonas) |
| Synonyms | AA407659, Image:3588380, MGC5139, POC7B, RGD1309359, unc-119 lipid binding chaperone B |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human UNC119B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- GMP-PDE, delta subunit
- lipid binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- ciliary transition zone
- cilia
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human UNC119B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cilium morphogenesis
- nervous system development
- lipoprotein transport
Cellular Component
Where in the cell the gene product is active
- cilium
- cytosol
- ciliary transition zone
Molecular Function
What the gene product does at the molecular level
- protein binding
- lipid binding