SLC38A9 Gene Summary [Human]
Enables L-arginine transmembrane transporter activity and L-leucine transmembrane transporter activity. Involved in amino acid transmembrane transport; cellular response to amino acid stimulus; and positive regulation of TOR signaling. Located in late endosome and lysosomal membrane. Is integral component of lysosomal membrane. Colocalizes with Ragulator complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Retained Intron |
| Official Symbol | SLC38A9 |
| Official Name | solute carrier family 38 member 9 [Source:HGNC Symbol;Acc:HGNC:26907] |
| Ensembl ID | ENSG00000177058 |
| Bio databases IDs | |
| Aliases | solute carrier family 38 member 9 |
| Synonyms | 4833412L08Rik, 6720411P22Rik, 9130023D20RIK, 9430067K09Rik, A730092C09, AI848218, RGD1311881, SNAT9, solute carrier family 38 member 9, solute carrier family 38, member 9, URLC11 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SLC38A9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- cholesterol binding
- leucine transporter
- asparagine transporter
- glutamine transporter
- L-amino acid transporter
- protein binding
- basic amino acid transporter
- amino acid binding
- organic cation transporter
- binding protein
- guanyl-nucleotide exchange factor
- Solute carrier families 5 and 6-like; solute binding domain
- amino acid transporter
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- lysosome
- lysosome membrane
- late endosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SLC38A9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- glutamine transport
- cellular response to amino acid stimulus
- asparagine transport
- branched-chain aliphatic amino acid transport
- positive regulation of TOR signaling cascade
- amino acid transmembrane transport
Cellular Component
Where in the cell the gene product is active
- late endosome membrane
- late endosome
- Ragulator complex
- lysosomal membrane
- lysosome
Molecular Function
What the gene product does at the molecular level
- sterol sensor activity
- arginine binding
- L-amino acid transmembrane transporter activity
- protein binding
- cholesterol binding
- metal ion binding
- L-glutamine transmembrane transporter activity
- guanyl-nucleotide exchange factor activity
- amino acid transmembrane transporter activity
- L-asparagine transmembrane transporter activity
- L-leucine transmembrane transporter activity