B3GNT8 Gene Summary [Human]
Enables protein N-acetylglucosaminyltransferase activity. Involved in poly-N-acetyllactosamine biosynthetic process. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | B3GNT8 |
| Official Name | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 [Source:HGNC Symbol;Acc:HGNC:24139] |
| Ensembl ID | ENSG00000177191 |
| Bio databases IDs | |
| Aliases | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 |
| Synonyms | B3GALT7, B7galt7, beta3Gn-T8, BGALT15, UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8, UDP-GlcNAc:betaGal β-1,3-N-acetylglucosaminyltransferase 8 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human B3GNT8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- UDP-galactose beta-N-acetylglucosamine beta-1,3-galactosyltransferase
- galactosyltransferase
- enzyme
- protein binding
- protein N-acetylglucosaminyltransferase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human B3GNT8 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein O-linked glycosylation
- O-glycan processing
- poly-N-acetyllactosamine biosynthetic process
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- Golgi membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- protein N-acetylglucosaminyltransferase activity
- UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity